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All donators of $10 or more will never see an advert on our site again!
Dean is struggling to deal with crazy Cas. Sam is over protective of the angel completely sucked in by Cas's apparent loss of sanity.
Dean can see through the mask. He knows Cas better than anyone. The isn't insanity, its a security blanket that Cas is using to avoid dealing with his actions.
When Cas hands him his angel blade and asks Dean to kill him. Dean has to act to save his friend from himself, force Cas to deal with his actions and mend their broken relationship.